{"id":3668,"date":"2022-04-21T10:49:09","date_gmt":"2022-04-21T14:49:09","guid":{"rendered":"https:\/\/www.upr.edu\/iii-cayey\/?post_type=dt_team&p=3668"},"modified":"2024-02-22T14:49:42","modified_gmt":"2024-02-22T18:49:42","slug":"ruth-b-pietri-melendez-ph-d","status":"publish","type":"dt_team","link":"https:\/\/www.upr.edu\/iii-cayey\/dt_team\/ruth-b-pietri-melendez-ph-d\/","title":{"rendered":"Ruth B. Pietri Mel\u00e9ndez"},"content":{"rendered":"

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T\u00edtulo\/Appointment: Catedr\u00e1tica Asociada
\nDepartamento\/Department: Qu\u00edmica
\nInstituci\u00f3n\/Institution: UPR-Cayey
\nE-mail: ruth.pietri@upr.edu
\nTel\u00e9fono\/Phone: (787) 738-2161, ext. 3033<\/p>\n

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Rese\u00f1a\/Biosketch:<\/strong>
\nLa Dra. Ruth Pietri es Catedr\u00e1tica Asociada en el Departamento de Qu\u00edmica de la Universidad de Puerto Rico en Cayey donde ofrece cursos de Qu\u00edmica General, Bioqu\u00edmica, Temas Especiales en Qu\u00edmica y Experiencias Interdisciplinarias de Investigaci\u00f3n para Estudiantes. Complet\u00f3 su doctorado en Qu\u00edmica Aplicada con especialidad en Biof\u00edsica en la Universidad de Puerto, Recinto Universitario de Mayag\u00fcez. Adem\u00e1s, posee un postdoctorado en el \u00e1rea de Biof\u00edsica del Laboratorio Nacional de Brookhaven, N.Y.<\/p>\n

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\u00c1reas de investigaci\u00f3n\/Research Interests:<\/strong>
\nSu inter\u00e9s investigativo est\u00e1 enfocado al estudio estructural de prote\u00ednas envueltas en enfermedades neurodegenerativas usando t\u00e9cnicas qu\u00edmico-f\u00edsicas. Actualmente trabaja con el proyecto titulado: Role of H2S in Superoxide Dismutase and its Implication in Fibrils Formation.<\/p>\n

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Publicaciones\/Publications:<\/strong>
\nHa publicado m\u00e1s de veinte art\u00edculos cient\u00edficos en revistas arbitradas por pares con factores de impactos sobresalientes. Adem\u00e1s, ha presentado los hallazgos cient\u00edficos obtenidos a nivel nacional e internacional. Tambi\u00e9n, ha obtenido una red de colaboradores cient\u00edficos en Estados Unidos y Europa, como resultados de las colaboraciones en investigaciones con el Laboratorio Nacional de Brookhaven en Nueva York, la Escuela de Medicina de Albert Einstein en Nueva York, en la Universidad Polit\u00e9cnica de Lausanne en Suiza y en la Universidad Polit\u00e9cnica de Francia.<\/p>\n

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  1. \n
      \n
    1. C. Rullan-Lind, R. Pietri, M. V\u00e1zquez-Cintr\u00f3n and A. Baerga-Ortiz. Artificial covalent linkage of acyl carrier proteins and fatty acid production (2019). Sci Rep. Nov 5;9(1):16011.<\/li>\n
    2. C. Rullan-Lind, R. Pietri, M. V\u00e1zquez-Cintr\u00f3n and A. Baerga-Ortiz. Fused dimerization increases expression, solubility, and activity of bacterial dehydratase enzymes. (2018). Protein Science, May; 27(5) 969-975<\/li>\n
    3. R. D\u00edaz-Ayala, L. Torres-Gonza\u0301lez, R. Pietri, C. Cabrera and J. L\u00f3pez_Garriga. Engineered (Lys)6\u2011Tagged Recombinant Sul\ufb01de-Reactive Hemoglobin I for Covalent Immobilization at Multiwalled Carbon Nanotubes. (2017) ACS Omega. 2, 9021-9032.<\/li>\n
    4. E. Rom\u00e1n, E. L\u00f3pez, R. Pietri and J. L\u00f3pez_Garriga. Sulfmyoglobin Conformational Change: A Role in the Decrease of Oxy-Myoglobin Functionality. (2016) Biochemistry and Biophysics Reports. 7, 386-393.<\/li>\n
    5. R. D\u00edaz-Ayala, A. Moya Rodr\u00edguez, R. Pietri, C. L. Cadilla and J. L\u00f3pez Garriga. Molecular Cloning and Characterization of a (Lys)6-Tagged Sulfide-Reactive Hemoglobin I from Lucina pectinata. (2015) Molecular Biotechnology. 57(11-12):1050-62.<\/li>\n
    6. B. R\u00edos-Gonz\u00e1lez, E. Rom\u00e1n-Morales, R. Pietri, J-L Garriga. Hydrogen Sulfide Activation in Hemeproteins: The Sulfheme Scenario. (2014) Journal of Inorganic Biochemistry. 133, 78-86.<\/li>\n
    7. C. Ramos-Alvarez, B-K. Yoo, R. Pietri, I. Lamarre, J-L. Martin, J-L.Garriga and M. Negrerie. Reactivity and dynamics of H2S, NO and O2 interacting with hemoglobins from Lucina pectinata (2013) Biochemistry. 52, 7007-21.<\/li>\n
    8. R. Pietri, S. Zerbs, D.M. Corgliano, M. Allaire, F.R. Collart, L.M. Miller. Biophysical and Structural Characterization of a Sequence-diverse Set of Solute-binding Proteins for Aromatic Compounds. (2012) J Biol Chem. 287, 23748-56.<\/li>\n
    9. V. Stojanoff, P. Northrup, R. Pietri, Zhong Z. Synchrotron radiation in life sciences. (2012) Protein Pept Lett. 19, 761-9<\/li>\n
    10. R. Pietri, E. Rom\u00e1n-Morales, and J. L\u00f3pez-Garriga. Hydrogen Sulfide and hemeproteins: knowledge and mysteries. (2011) Antioxid Redox Signal. 15, 393-404.<\/li>\n
    11. E. Rom\u00e1n-Morales, R. Pietri R, B. Ramos-Santana, S.N. Vinogradov, A. Lewis-Ballester, and J. L\u00f3pez-Garriga. Structural determinants for the formation of sulfhemeprotein complexes. (2010) Biochem Biophys Res Commun. 400, 489-92.<\/li>\n
    12. C. Ramos, R. Pietri, W. Lorenzo, E. Roman, L.B. Granell, C.L. Cadilla, and J. L\u00f3pez-Garriga. Recombinant hemoglobin II from Lucina pectinata: a large-scale method for hemeprotein expression in E. coli. (2010) Protein J. 29, 143-51.<\/li>\n
    13. R. Pietri, A. Lewis, R.G. Le\u00f3n, G. Casabona, L. Kiger, S.R. Yeh, S. Fernandez-Alberti, M.C. Marden, C.L. Cadilla, and J. L\u00f3pez-Garriga. Factors controlling the reactivity of hydrogen sulfide with hemeproteins. (2009) Biochemistry, 48, 4881-94.<\/li>\n
    14. E. Ramirez, A. Cruz, D. Rodriguez, L. Uchima, R. Pietri, A. Santana, J. L\u00f3pez-Garriga, and J. L\u00f3pez, G.E. Effects of active site mutations in Hemoglobin I from Lucina pectinata: A molecular dynamic study. (2008) Molecular Simulations, 34, 715-725.<\/li>\n
    15. J. Gavira, A. Camara-Artigas, W. De Jesus, R. Pietri, A. Lewis, S-R Yeh, J. L\u00f3pez-Garriga, and J.M. Garc\u00eda-Ruiz. Structure and ligand selection of hemoglobin II from L. pectinata. (2008) J. Biol. Chem. 283, 9414-9423.<\/li>\n
    16. R. Pietri, L. Granell, R. Le\u00f3n, C. Cadilla, and J. L\u00f3pez-Garriga. Hemoglobin I from Lucina pectinata: A model for distal heme-ligand control. (2006) Biochimica et Biophysica Acta -Proteins and Proteomics, 1764, 758-765.<\/li>\n
    17. R. Pietri, L. Granell, A.Cruz, W. De Jes\u00fas, Ariel Lewis, J. L\u00f3pez Garriga, R. Leon and C. Cadilla. Tyrosine B10 and Heme-Ligand Interaction in the Hemoglobin II from Lucina pectinata. Control of heme reactivity. (2005) BBA, 1747, 195-203.<\/li>\n
    18. E. Collazo, R. Pietri, W. De Jes\u00fas, C. Ramos, A. Del Toro, R. Le\u00f3n, J. L\u00f3pez Garriga, and C. L. Cadilla. Functional Characterization of the Purified Holo Form of Hemoglobin I from Lucina pectinata Over-Expressed in Escherichia coli. (2004) Protein Journal, 23, 239-245.<\/li>\n
    19. J. Helbing, J. Bredenbeck, P. Hamm, L. Bonacita, F. van Mourik, F. Chaussard, A. Gonzalez-Gonzalez, M. Chergui, R. Pietri, C. Ruiz C. Ramos, and J. L\u00f3pez Garriga. Time-resolved visible and infrared study of the cyano complexes of Myoglobin and Hemoglobin I from Lucina pectinata. (2004) Biophysical Journal, 87, 1-11.<\/li>\n
    20. R. Le\u00f3n, H. Munier-Lehmann, O. Barzu, V. Baudin Creuza, R. Pietri, J. L\u00f3pez-Garriga and C. Cadilla. High-level production of recombinant wild type and mutant sulfide-reactive hemoglobin I (HbI) from Lucina pectinata in Escherichia coli. (2004) Protein Expression and Purification, 38, 184-195.<\/li>\n
    21. L. Saliceti, R. Buxeda, J. L\u00f3pez-Garriga, R. Pietri and E. Collazo. Transformation of the Teaching Methodology in a Laboratory Course of the Industrial Biotechnology Curriculum in Response to the Student Profile. (2003) ICEE Proceedings, Chapter XX.<\/li>\n
    22. R. Pietri, C. Ramos, E. Ram\u00edrez, J. Helbing, M. Chergui, and J. L\u00f3pez Garriga. Investigation of the Hemoglobin I Carbonmonoxide and Oxy Complexes from Lucina pectinata by Femtosecond Transient Absorption. Femtochemistry and Femtobiology (World Scientific Publishing House, Douhal and Santamaria Ed.) (2002), 720-730.<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

        T\u00edtulo\/Appointment: Catedr\u00e1tica Asociada Departamento\/Department: Qu\u00edmica Instituci\u00f3n\/Institution: UPR-Cayey E-mail: ruth.pietri@upr.edu Tel\u00e9fono\/Phone: (787) 738-2161, ext. 3033   Rese\u00f1a\/Biosketch: La Dra. Ruth Pietri es Catedr\u00e1tica Asociada en el Departamento de Qu\u00edmica de la Universidad de Puerto Rico en Cayey donde ofrece cursos de Qu\u00edmica General, Bioqu\u00edmica, Temas Especiales en Qu\u00edmica y Experiencias Interdisciplinarias de Investigaci\u00f3n para Estudiantes.…<\/p>\n","protected":false},"featured_media":3669,"template":"","dt_team_category":[16],"class_list":["post-3668","dt_team","type-dt_team","status-publish","has-post-thumbnail","hentry","dt_team_category-investigadores","dt_team_category-16","description-off"],"_links":{"self":[{"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/dt_team\/3668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/dt_team"}],"about":[{"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/types\/dt_team"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/media\/3669"}],"wp:attachment":[{"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/media?parent=3668"}],"wp:term":[{"taxonomy":"dt_team_category","embeddable":true,"href":"https:\/\/www.upr.edu\/iii-cayey\/wp-json\/wp\/v2\/dt_team_category?post=3668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}